4-(Trifluoromethyl)picolinic acid, 2-Carboxy-4-(trifluoromethyl)pyridine - Names and Identifiers
4-(Trifluoromethyl)picolinic acid, 2-Carboxy-4-(trifluoromethyl)pyridine - Physico-chemical Properties
Molecular Formula | C7H4F3NO2
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Molar Mass | 191.11 |
Density | 1.484±0.06 g/cm3(Predicted) |
Melting Point | 159-161°C |
Boling Point | 293.6±40.0 °C(Predicted) |
Flash Point | 131.4°C |
Vapor Presure | 0.000777mmHg at 25°C |
pKa | 3.21±0.10(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.475 |
4-(Trifluoromethyl)picolinic acid, 2-Carboxy-4-(trifluoromethyl)pyridine - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S51 - Use only in well ventilated areas.
S38 - In case of insufficient ventilation, wear suitable respiratory equipment.
S36/37 - Wear suitable protective clothing and gloves.
S24/25 - Avoid contact with skin and eyes.
S22 - Do not breathe dust.
S7/9 -
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WGK Germany | 3 |
Hazard Class | IRRITANT |
4-(Trifluoromethyl)picolinic acid, 2-Carboxy-4-(trifluoromethyl)pyridine - Introduction
4-(Trifluoromethyl)pyridine-2-carboxylic acid is an organic compound whose chemical formula is C7H4F3NO2.
Nature:
-Appearance: 4-(Trifluoromethyl)pyridine-2-carboxylic acid is a white to pale yellow solid.
-Melting point: about 122-126 degrees Celsius.
-Solubility: Soluble in ethanol and dimethyl sulfoxide (DMSO), slightly soluble in water.
Use:
- 4-(Trifluoromethyl)pyridine-2-carboxylic acid is often used as an intermediate in organic synthesis to synthesize other organic compounds.
-It can also be used as an intermediate for certain drugs in the pharmaceutical field.
Preparation Method:
The preparation of
- 4-(Trifluoromethyl)pyridine-2-carboxylic acid usually adopts chemical synthesis route. One such method is obtained by trifluoromethylating pyridone.
Safety Information:
- 4-(Trifluoromethyl)pyridine-2-carboxylic acid is irritating and corrosive during handling, and care should be taken to avoid contact with skin, eyes and mucous membranes.
-Take appropriate protective measures when using, such as wearing protective glasses and gloves, and ensure that the operation is carried out under well-ventilated conditions.
-It should be sealed in a dry, cool place when stored, away from fire and oxidizing agents.
Last Update:2024-04-09 02:00:47